Alexandra V Goldberg

Alexandra V. Goldberg is a Clinical Scientist, Clinical Research Dietitian and Clinical Trial Coordinator whose work connects nutrition science, translational medical research and hospital innovation. She holds a Master of Dietetics with First Class Honours and is registered with the Dietitians Board of New Zealand (Reg. 20-02273). Her research and clinical practice span gastrointestinal physiology, metabolic health, early-life nutrition and respiratory-related nutritional support, with a particular focus on the interactions between nutrition, immunity and microbial ecology in vulnerable populations.

As a Clinical Scientist, Alexandra focuses on translating mechanistic understanding into clinical application. She has extensive experience with highly complex gastrointestinal cases, including advanced assessment of feeding tolerance, interpretation of gastric motility, and the development of individualised enteral nutrition interventions. She has contributed to device-based clinical diagnostic trials, including the SMāRT Tube programme and Alimetry gastric mapping studies. These studies aim to improve diagnostic precision in gastric dysfunction and establish more evidence-based postoperative nutrition pathways for high-risk patients.

Alexandra’s research interests also extend to developmental and respiratory immunity, particularly in vulnerable populations experiencing recurrent respiratory infections or immune dysregulation. Her work examines the microbiome–respiratory axis, exploring how diet, microbial maturation and metabolites influence airway resilience, mucosal immunity and respiratory health outcomes. She contributes to the assessment of nutrient adequacy, microbial composition, key micronutrient patterns and early-life environmental factors, examining their effects on immune and respiratory regulation from molecular to clinical levels. Grounded in mechanistic evidence and clinical feasibility, her work translates scientific reasoning into practical clinical interventions.

Since joining Middlemore Clinical Trials in 2022, Alexandra has contributed to multiple Phase II and Phase III studies of cardiometabolic disease and cardiovascular outcomes, including the VER-201-PH2-301 BELIEVE programme and the Synchronize CVOT trial. Her responsibilities include participant assessment, protocol implementation, regulatory and ethics processes, safety monitoring, data quality and communication across stakeholders. She also helps ensure rigorous evaluation of nutrition-related biomarkers and mechanistic measures. Her combined clinical and research expertise enables close integration of healthcare delivery and scientific enquiry.

Alexandra has a strong academic foundation in medicinal chemistry, metabolism and nutritional biochemistry. At the University of Auckland, she completed a bachelor’s degree in medicinal chemistry (2018), a postgraduate diploma in nutrition and dietetics (2019), and a Master of Dietetics with First Class Honours (2022). This interdisciplinary training supports her understanding of metabolic regulation, biochemical pathways, drug–nutrient interactions and the scientific basis of targeted nutrition strategies, particularly mechanisms involving microbial development, immune regulation and respiratory vulnerability. Her systems-biology perspective views nutrition as an important means of influencing metabolic, immune and microbial networks.

Clinically, Alexandra is recognised for her expertise in designing and delivering advanced clinical nutrition interventions. She has supported the nutritional management of adults and children across postoperative recovery, chronic disease, recurrent respiratory infections, reduced feeding tolerance and developmental nutrition concerns. She integrates physiological, microbiological and metabolic data into individualised, evidence-based and actionable nutrition plans, combining scientific depth with clinical practicality.

Alexandra’s work reflects a forward-looking vision of clinical nutrition as a scientific discipline that integrates mechanistic insight, translational research and patient-centred practice. Whether presenting at academic conferences, contributing to multicentre clinical studies or developing clinical nutrition strategies for vulnerable populations, she is known for scientific rigour, conceptual clarity and a commitment to advancing evidence-based healthcare.

Alexandra remains active in New Zealand’s clinical nutrition and clinical research sectors, undertaking roles in scientific research, clinical care and translational methodology.

• Registered Dietitian — Dietitians Board of New Zealand

  Practises under the Health Practitioners Competence Assurance Act 2003 (Reg. 20-02273), adhering to national standards for safety, cultural competence and continuing professional development.

• Clinical Scientist & Clinical Research Dietitian — Middlemore Clinical Trials

  Contributes to cardiometabolic, gastrointestinal, respiratory-related nutrition and microbiome research, integrating nutritional endpoints with mechanistic outcomes.

• Clinical Trial Coordinator — Middlemore Clinical Trials

  Responsible for participant management, ethics and compliance processes, GCP documentation, data integrity and communication with international study partners.

• Gastrointestinal Nutrition & Enteral Physiology Specialist

  Expertise in feeding tolerance, interpretation of gastric motility—including Alimetry gastric mapping—and evidence-based nutritional support for complex gastrointestinal cases.

• Clinical Nutrition & Translational Research Network Member

  Collaborates with regional hospitals and academic teams on nutrition–microbiome–respiratory interactions, resilience phenotypes and the development of evidence-based interventions.

Alexandra provides advanced training for healthcare professionals using a framework of clinical physiology, microbiome science and nutritional intervention. Her structured, evidence-based and mechanism-focused approach supports professional development.

• Advanced Nutrition & Microbial Pathways Training

  Covers gut–lung physiology, dietary modulation of the microbiome, respiratory vulnerability and the design of targeted nutrition interventions across life stages.

• Clinical Trials & Research Methodology Training

  Includes protocol design, informed consent, nutritional endpoints, safety monitoring, data interpretation and GCP documentation standards.

• Gastrointestinal & Enteral Nutrition Courses

  Focuses on gastric emptying and physiology, strategies for advancing feeding, diagnostic interpretation and evidence-based nutrition interventions for complex gastrointestinal patients.

• Performance Physiology & Metabolic Nutrition Courses

  Covers energy periodisation, muscle physiology, metabolic adaptation and behaviour-change strategies across developmental stages.

• Evidence-Based Supplements & Formulation Science

  Drawing on her chemistry and clinical science background, teaches mechanisms of action, dosing principles, quality standards and nutrition–pharmacology interactions.